Rescue Hearing’s initial gene therapy product will target a genetic mutation known to cause progressive hearing loss which eventually leads to deafness.
New enabling technologies are on the verge of making significant clinical impact:
- Gene editing tools like CRISPR / Cas9 is making the development of gene therapy products realistic, efficient and affordable;
- Consumer cost for genetic testing is going down making identification of causative genetic mutations reliable, realistic and affordable;
- New technologies for hearing loss are developing at a rapid rate enhancing our ability to develop new products;
- There are currently no approved therapies for hearing loss
- The worldwide hearing loss market is growing (466 million people with disabling hearing loss)(1)
- Investment in Gene and Cell therapy companies is increasing. In 2015, total financings in gene and cell therapy companies totaled $10.8 billion, which represented a 106% increase over 2014. Big pharma and big Medtech are the driving forces(2)
Vision: Eliminate Hearing Loss as a Chronic Condition
Mission: Develop technologies across the disciplines of therapeutics, diagnostics, and imaging.
The RHI vision is to “Eliminate Hearing Loss as a Chronic Condition”. To achieve our vision, we will seek to develop an array of technologies across the disciplines of therapeutics, diagnostics and imaging.
In 2005, Xavier was born. As with most newborns, he received a newborn hearing screening test which he failed. Xavy’s parents were devastated but moved forward as best they could. What followed over the next 4 yrs were chronic ear infections, multiple medications and numerous trips to hearing specialists. None of the clinicians were able to explain the chronic ear infections or the cause of Xavy’s hearing loss. Despite his chronic ear infections and abnormal hearing, Xavy was exceptionally bright, insatiably curious and did not experience any delays in language or speech.
In 2010 at 5 years of age, Xavy was diagnosed with Bi Lateral Sensorineural hearing loss (SNHL) nonsyndromic. He was fitted for hearing aids and told he would wear them for the rest of his life. Xavy started school and was the kid in the front of the class wearing the hearing aids with the brightly colored ear molds.
Get to know us
ABOUT THE FOUNDER
As Father of a 15-year-old son born with genetic hearing loss, Mr. Ayala created RHI to achieve this vision “Eliminate Hearing Loss as a Chronic Condition”.